Symbol Name ID |
Ets1
E26 avian leukemia oncogene 1, 5' domain MGI:95455 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | hematopoietic system phenotype |
increased B cell apoptosis |
decreased thymocyte apoptosis |
increased splenocyte apoptosis |
decreased B cell proliferation |
decreased T cell proliferation |
abnormal thymus morphology |
abnormal thymus subcapsular epithelium morphology |
abnormal thymus cortex morphology |
increased thymus weight |
enlarged thymus |
thymus hypoplasia |
decreased thymocyte number |
abnormal lymphopoiesis |
abnormal B cell differentiation |
decreased pro-B cell number |
increased pro-B cell number |
abnormal CD8-positive, alpha-beta T cell differentiation |
increased double-negative T cell number |
increased double-positive T cell number |
decreased mature B cell number |
absent B-1a cells |
increased plasma cell number |
decreased B cell number |
decreased NK cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased memory T cell number |
decreased T cell number |
decreased leukocyte cell number |
abnormal CD8-positive, alpha beta T cell morphology |
abnormal spleen morphology |
abnormal spleen red pulp morphology |
decreased spleen weight |
small spleen |
abnormal leukocyte physiology |
abnormal NK cell physiology |
impaired natural killer cell mediated cytotoxicity |
abnormal T cell activation |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
Ets1tm1.1Dds/Ets1tm1.1Dds | ||||||||||||||||||||||||||||||||||||||||
Ets1tm1Fwa/Ets1tm1Fwa | ||||||||||||||||||||||||||||||||||||||||
Ets1tm1Jml/Ets1tm1Jml | ||||||||||||||||||||||||||||||||||||||||
Ets1tm2Jml/Ets1tm2Jml | * | |||||||||||||||||||||||||||||||||||||||
Ets1tm1.1Dds/Ets1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|